2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone CAS: 86404-63-9

Product Parameters
Catalog No. BK12MB
CAS.RN 86404-63-9
Molecular Formula C10H7F2N3O
Molecular Weight 223.18 g/mol
Purity NLT 98%
Product Overview

Difluorotriazole acetophenone (CAS No.: 86404-63-9) is an important pharmaceutical intermediate widely used in the synthesis of the antifungal drug fluconazole, serving as a key structural unit. This product exhibits good chemical stability and reactivity, making it suitable for various stages of drug development, small-scale preparation, pilot-scale amplification, and commercial production. Its core application lies in providing an efficient synthetic route for fluconazole and other triazole antifungal drugs, meeting the pharmaceutical companies' demand for high-purity, high-quality intermediates, and contributing to new drug development and process optimization.

Applications
  • Synthesis of fluconazole active pharmaceutical ingredient
  • Preparation of intermediates for triazole antifungal drugs
  • Custom compound development for pharmaceutical R&D laboratories
  • Process route optimization and scale-up production
  • Drug impurity research and analysis
Quality & Supply Capability

English Name: 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone Properties: White to off-white crystalline powder containing two fluorine atoms and one triazole group. It exhibits good thermal and chemical stability and is suitable for various organic synthesis reactions. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Simultaneously, we have a professional technical team to provide customers with comprehensive technical support from laboratory research and development to industrial production, helping customers efficiently advance process development, route optimization, and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing a rich product line and professional experience. Full-scale supply capabilities, covering needs from laboratory to commercial production. Provides complete quality control documentation to ensure controllable and traceable product quality. Supports customized requirements, adjusting purity, impurity standards, and packaging as needed. Provides supporting process optimization and scale-up technologies to enhance clients' R&D efficiency and production conversion capabilities.

Intermediates of Voriconazole
Catalog No. Product Name CAS
BA34AR Voriconazole API 137234-62-9
BK34JG 4-Ethyl-5-fluoro-6-hydroxypyrimidine 137234-87-8
BK3N15 4-Chloro-6-ethyl-5-fluoropyrimidine 137234-74-3
BK91L7 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine 188416-28-6
BK8P8B 2-Fluoro-3-oxopentanoic acid ethyl ester 759-67-1
BK1RZ4 Formamidine acetate 3473-63-0
BK12MB 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone 86404-63-9
BK6Q31 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 188416-35-5
BK20C1 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 182230-43-9
BK81C8 5-Fluoropyrimidine 675-21-8
BK36N5 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
BK8FH7 2,4-Dichloro-6-ethyl-5-fluoropyrimidine 137234-85-6
BK98Q6 2-Chloro-2',4'-difluoroacetophenone 51336-94-8
BK4Z7G 1,5-Anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol 454475-43-5
BK7D64 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-85-6
BK556P 4-Bromo-5-fluoropyrimidine 1003706-87-3
BK453P Methyltriphenylphosphonium bromide 1779-49-3
BK3N73 1H-1,2,4-Triazole 288-88-0
BK0T02 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride 188416-20-8
BK14Q1 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-83-4
BK72M1 (2R,3S)-3-(4-Bromo-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-65-1
BK5XX4 (2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-66-2
BK487S (2R,3S)-3-(5-Fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-67-3
BK38DY (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)butan-2-ol 1474024-68-4
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