(2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride CAS: 188416-35-5

Product Parameters
Catalog No. BK6Q31
CAS.RN 188416-35-5
Molecular Formula C16H13ClF3N5O
Molecular Weight 383.76 g/mol
Purity NLT 98%
Synonyms 6-Chloro-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
Product Overview

This product is a complex pharmaceutical intermediate with the chemical name (2R,3S/2S,3R)-3-(4-chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)-2-butanol hydrochloride. It is widely used in the synthesis of antiviral drugs and nucleoside compounds, and is suitable for the research and development stage, small-scale testing, pilot-scale optimization and industrial-scale production. It is a key starting material for constructing specific molecular skeletons, and has high structural specificity and reactivity, which can meet the requirements of high purity and high stability for the development of multiple drug categories.

Applications
  • Key intermediates in antiviral drug synthesis
  • Precursors for nucleoside analog drug structure modification
  • Core raw materials for drug molecule skeleton construction
  • Customized synthesis support for pharmaceutical R&D projects
  • Process route optimization and scale-up production support
Quality & Supply Capability

English Name: (2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Properties: This product is a mixture of stereoisomers with a fluorinated heterocyclic structure, exhibiting good thermal and chemical stability. Containing multiple functional groups, it is suitable for various organic synthesis reactions, demonstrating high reactivity and selectivity. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from laboratory sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust purity standards, impurity control schemes, packaging specifications, and delivery cycles according to customer needs, while also providing a complete quality documentation system to ensure product compliance with GMP and ICH regulations. We also provide comprehensive technical support from laboratory research and development to industrial production, helping customers to efficiently advance process development, route optimization, and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, with extensive experience in supplying nucleoside and drug synthesis intermediates. Full-scale supply capability covering samples, gram-level, kilogram-level to commercial-scale production. Provides complete quality control documentation, including COA, MSDS, HPLC, NMR, etc. Supports customized needs, adjusting purity, impurity control, and packaging specifications according to customer requirements. Provides process optimization and scale-up technical support to help customers smoothly transition from R&D to production.

Intermediates of Voriconazole
Catalog No. Product Name CAS
BA34AR Voriconazole API 137234-62-9
BK34JG 4-Ethyl-5-fluoro-6-hydroxypyrimidine 137234-87-8
BK3N15 4-Chloro-6-ethyl-5-fluoropyrimidine 137234-74-3
BK91L7 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine 188416-28-6
BK8P8B 2-Fluoro-3-oxopentanoic acid ethyl ester 759-67-1
BK1RZ4 Formamidine acetate 3473-63-0
BK12MB 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone 86404-63-9
BK6Q31 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 188416-35-5
BK20C1 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 182230-43-9
BK81C8 5-Fluoropyrimidine 675-21-8
BK36N5 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
BK8FH7 2,4-Dichloro-6-ethyl-5-fluoropyrimidine 137234-85-6
BK98Q6 2-Chloro-2',4'-difluoroacetophenone 51336-94-8
BK4Z7G 1,5-Anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol 454475-43-5
BK7D64 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-85-6
BK556P 4-Bromo-5-fluoropyrimidine 1003706-87-3
BK453P Methyltriphenylphosphonium bromide 1779-49-3
BK3N73 1H-1,2,4-Triazole 288-88-0
BK0T02 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride 188416-20-8
BK14Q1 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-83-4
BK72M1 (2R,3S)-3-(4-Bromo-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-65-1
BK5XX4 (2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-66-2
BK487S (2R,3S)-3-(5-Fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-67-3
BK38DY (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)butan-2-ol 1474024-68-4
Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
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