(2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol CAS: 1474024-66-2

Product Parameters
Catalog No. BK5XX4
CAS.RN 1474024-66-2
Molecular Formula C14H12ClF3N2O
Molecular Weight 316.71 g/mol
Purity NLT 98%
Product Overview

(2R,3S)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)but-2-ol is a well-defined pharmaceutical intermediate widely used in the synthesis of nucleoside analogs and antiviral drugs. This compound exhibits high stereoselectivity, making it suitable for key steps in drug molecule skeleton construction and functional group introduction. It can meet the needs of multiple stages, from R&D and pilot-scale production to large-scale production, and is an important precursor in the development of novel antiviral drugs.

Applications
  • Nucleoside analogue synthesis
  • Preparation of antiviral drug intermediates
  • Drug molecule skeleton construction
  • Custom synthesis for pharmaceutical R&D projects
  • Process route optimization and scale-up production
Quality & Supply Capability

English Name: (2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol Properties: This product is a white to off-white solid with a stable cyclic structure and specific fluorinated functional groups. It exhibits good chemical stability and reactivity, making it suitable for various organic synthesis pathways. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific requirements. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Simultaneously, we have a professional technical support team to assist customers in completing the entire process from laboratory research and development to industrial scale-up, ensuring smooth process development and facilitating efficient project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, with extensive experience in nucleoside compound synthesis. Full-scale supply capability, covering all stages from laboratory to commercial production. Provides complete quality control documentation, including COA, MSDS, HPLC, NMR, etc. Supports customized needs, enabling process adjustments and product optimization based on specific customer requirements. Comprehensive process optimization and scale-up technical support to ensure efficient R&D and production for our clients.

Intermediates of Voriconazole
Catalog No. Product Name CAS
BA34AR Voriconazole API 137234-62-9
BK34JG 4-Ethyl-5-fluoro-6-hydroxypyrimidine 137234-87-8
BK3N15 4-Chloro-6-ethyl-5-fluoropyrimidine 137234-74-3
BK91L7 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine 188416-28-6
BK8P8B 2-Fluoro-3-oxopentanoic acid ethyl ester 759-67-1
BK1RZ4 Formamidine acetate 3473-63-0
BK12MB 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone 86404-63-9
BK6Q31 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 188416-35-5
BK20C1 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 182230-43-9
BK81C8 5-Fluoropyrimidine 675-21-8
BK36N5 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
BK8FH7 2,4-Dichloro-6-ethyl-5-fluoropyrimidine 137234-85-6
BK98Q6 2-Chloro-2',4'-difluoroacetophenone 51336-94-8
BK4Z7G 1,5-Anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol 454475-43-5
BK7D64 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-85-6
BK556P 4-Bromo-5-fluoropyrimidine 1003706-87-3
BK453P Methyltriphenylphosphonium bromide 1779-49-3
BK3N73 1H-1,2,4-Triazole 288-88-0
BK0T02 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride 188416-20-8
BK14Q1 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-83-4
BK72M1 (2R,3S)-3-(4-Bromo-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-65-1
BK5XX4 (2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-66-2
BK487S (2R,3S)-3-(5-Fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-67-3
BK38DY (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)butan-2-ol 1474024-68-4
Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
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