3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride CAS: 188416-20-8

Product Parameters
Catalog No. BK0T02
CAS.RN 188416-20-8
Molecular Formula C16H14Cl2F3N5O
Molecular Weight 420.22 g/mol
Purity NLT 98%
Product Overview

3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)but-2-ol hydrochloride is a structurally complex pharmaceutical intermediate widely used in the synthesis of innovative drugs such as antiviral and antitumor agents. This product possesses a well-defined chemical structure and stable physicochemical properties, making it suitable for the early stages of drug development, including molecular construction and subsequent process optimization. It can meet the needs of various scenarios, from laboratory-scale and pilot-scale production to commercial manufacturing, and is one of the important raw materials for pharmaceutical companies in new drug development and process improvement.

Applications
  • Key intermediates in antiviral drug synthesis
  • Construction of molecular skeletons for antitumor drugs
  • Construction and screening of pharmaceutical compound libraries
  • Research and optimization of process routes
  • Development of customized drug intermediates
Quality & Supply Capability

English Name: 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride Properties: Contains a pyrimidine ring, a triazole ring, and a fluorophenyl structure, exhibiting good reactivity and stability, suitable for various organic synthesis reaction systems. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. Our company can provide a full-process service from sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Meanwhile, we have a professional technical team to provide customers with comprehensive technical support from laboratory research and development to large-scale production, helping customers to efficiently advance process development, route optimization and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, with extensive experience in product development and supply. Full-scale supply capabilities, covering all stages from sample production to commercial manufacturing. Provides complete quality control documentation to ensure controllable product quality. Supports customized needs, meeting individualized process development and product design requirements. Provides process optimization technical support to help customers improve synthesis efficiency and yield.

Intermediates of Voriconazole
Catalog No. Product Name CAS
BA34AR Voriconazole API 137234-62-9
BK34JG 4-Ethyl-5-fluoro-6-hydroxypyrimidine 137234-87-8
BK3N15 4-Chloro-6-ethyl-5-fluoropyrimidine 137234-74-3
BK91L7 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine 188416-28-6
BK8P8B 2-Fluoro-3-oxopentanoic acid ethyl ester 759-67-1
BK1RZ4 Formamidine acetate 3473-63-0
BK12MB 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone 86404-63-9
BK6Q31 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 188416-35-5
BK20C1 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 182230-43-9
BK81C8 5-Fluoropyrimidine 675-21-8
BK36N5 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
BK8FH7 2,4-Dichloro-6-ethyl-5-fluoropyrimidine 137234-85-6
BK98Q6 2-Chloro-2',4'-difluoroacetophenone 51336-94-8
BK4Z7G 1,5-Anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol 454475-43-5
BK7D64 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-85-6
BK556P 4-Bromo-5-fluoropyrimidine 1003706-87-3
BK453P Methyltriphenylphosphonium bromide 1779-49-3
BK3N73 1H-1,2,4-Triazole 288-88-0
BK0T02 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride 188416-20-8
BK14Q1 3-Chloro-2-(2,4-difluorophenyl)-2-(trimethylsilyloxy)propanal 861718-83-4
BK72M1 (2R,3S)-3-(4-Bromo-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-65-1
BK5XX4 (2R,3S)-3-(4-Chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-66-2
BK487S (2R,3S)-3-(5-Fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol 1474024-67-3
BK38DY (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)butan-2-ol 1474024-68-4
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Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
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