3-Chloro-4-fluoroaniline CAS: 367-21-5

Product Parameters
Catalog No. BK57LQ
CAS.RN 367-21-5
Molecular Formula C6H5ClFN
Molecular Weight 145.56 g/mol
Purity NLT 98%
Product Overview

3-Chloro-4-fluoroaniline is an important pharmaceutical intermediate widely used in the synthesis of antitumor, antiviral, and cardiovascular drugs. It has high reactivity and structural specificity, making it suitable for new drug development, process optimization, and large-scale production. It can meet the diverse needs of laboratory small-scale, pilot-scale, and commercial production, and is one of the important raw materials in the field of pharmaceutical chemical synthesis.

Applications
  • Used for the construction and modification of antitumor drug molecular structures
  • Participates in the synthetic pathway as a key intermediate for antiviral drugs
  • Serves as a core skeleton compound in cardiovascular drug development
  • Supports the process development of novel antibiotics and antibacterial drugs
  • Used for the design and optimization of customized organic synthetic routes
Quality & Supply Capability

English Name: 3-Chloro-4-fluoroaniline Properties: White to pale yellow crystalline powder, readily soluble in organic solvents such as ethanol and acetone. It exhibits good thermal and chemical stability. Containing chlorine and fluorine substituents, it possesses high reactivity and selectivity. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific details. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. We also provide technical support from laboratory R&D to scale-up production, helping customers complete process development, route optimization, and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing extensive product portfolio and technological reserves. Full-scale supply capabilities covering needs from laboratory to industrial production. Provides complete quality control documentation to ensure controllable and traceable product quality. Customized synthesis and process optimization can be implemented according to customer requirements. Support for scale-up production technology to ensure smooth process transformation and implementation.

Intermediates of Afatinib
Catalog No. Product Name CAS
BA70B4 Afatinib API 850140-72-6
BK45Q2 (E)-4-(dimethylamino)but-2-enoic acid Hydrochloride 1130155-48-4
BK0P7B 2-(Dimethylamino)acetaldehyde 52334-92-6
BK26A4 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-17-1
BK57LQ 3-Chloro-4-fluoroaniline 367-21-5
BK9PS5 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 314771-76-1
BK6VV7 Methyl 3-amino-4-hydroxybenzoate 536-25-4
BK342Z (E)-4-(Dimethylamino)but-2-enoyl chloride 1056149-69-9
BK5Z6K 4-Hydroxybenzonitrile 767-00-0
BK9K90 4-Hydroxy-3-nitrobenzonitrile 3272-08-0
BK2Q99 6-Nitro-7-fluoro-4-hydroxyquinazoline 162012-43-3
BK853Z (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-18-2
BK1A2M 2-Amino-4-fluoro-5-nitrobenzoic acid 1194097-41-0
BK04ZE N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine 314771-88-5
BK5L94 (E)-4-Bromobut-2-enoic acid 13991-36-1
BK3G98 (E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)but-2-enamide 1454655-89-0
BK82EZ (E)-4-((3-Chloro-4-fluorophenyl)amino)-7-fluoro-6-((4-(dimethylamino)but-2-enamido)quinazoline 1-oxide 1454656-00-8
BK2D23 (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1156986-96-7
BK75AW (S)-4-(Dimethylamino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide 1451008-28-8
BK8C2X (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451008-29-9
BK190V (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide mesylate 1451008-30-2
BK0T7T 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbamate 1451012-56-8
BK27ZJ (E)-4-(Dimethylamino)but-2-en-1-yl 4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbonate 1451012-57-9
BK6T31 7-Fluoro-4-((3-chloro-4-fluorophenyl)amino)-6-nitroquinazolin-3-ium chloride 1637330-92-7
BK0W74 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl 4-(dimethylamino)but-2-enoate 1637330-93-8
BK8Z98 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1-oxide 1451369-97-3
BK1K4D (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451369-98-4
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