N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine CAS: 314771-88-5

Product Parameters
Catalog No. BK04ZE
CAS.RN 314771-88-5
Molecular Formula C18H14ClFN4O4
Molecular Weight 404.78 g/mol
Purity NLT 98%
Product Overview

N-(3-chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a structurally complex pharmaceutical intermediate widely used in the synthesis of innovative drugs for antitumor and antiviral purposes. This compound possesses a well-defined molecular structure and stable chemical properties, making it suitable for structural modification and activity screening in the early stages of drug development. It can also be used for process optimization and quality control in small-scale, pilot-scale, and large-scale production stages. As a key starting material or intermediate, its purity, stability, and reproducibility have a significant impact on subsequent process development, making it an important supporting material for pharmaceutical companies in new drug research and industrialization.

Applications
  • Drug molecule structure modification and activity research
  • Key intermediates for antitumor drug synthesis
  • Support for antiviral drug process development
  • Customized synthesis services for pharmaceutical intermediates
  • Core starting materials in innovative drug development
Quality & Supply Capability

English Name: N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine Properties: This product is a white to off-white solid containing nitro, fluorine, chlorine, and tetrahydrofuranoxy functional groups. It exhibits good thermal and chemical stability and is suitable for various organic synthesis reaction systems. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging Document Support: COA, MSDS, HPLC, NMR, etc. Our company can provide a full-process supply service from laboratory samples to industrial batch production, covering small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Meanwhile, we have a professional technical team that can provide customers with comprehensive technical support from laboratory research and development to process scale-up, helping customers to achieve process optimization, route improvement and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing extensive synthesis experience and technological expertise. Full-scale supply capabilities to meet diverse needs from R&D to commercialization. Provides complete quality control documentation to ensure controllable and traceable product quality. Supports customized requirements, adjusting purity, impurity standards, and packaging according to customer specifications. Provides supporting process optimization and project scale-up technologies to enhance customer R&D efficiency and成果转化率 (commercialization rate).

Intermediates of Afatinib
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BA70B4 Afatinib API 850140-72-6
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BK0P7B 2-(Dimethylamino)acetaldehyde 52334-92-6
BK26A4 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-17-1
BK57LQ 3-Chloro-4-fluoroaniline 367-21-5
BK9PS5 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 314771-76-1
BK6VV7 Methyl 3-amino-4-hydroxybenzoate 536-25-4
BK342Z (E)-4-(Dimethylamino)but-2-enoyl chloride 1056149-69-9
BK5Z6K 4-Hydroxybenzonitrile 767-00-0
BK9K90 4-Hydroxy-3-nitrobenzonitrile 3272-08-0
BK2Q99 6-Nitro-7-fluoro-4-hydroxyquinazoline 162012-43-3
BK853Z (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-18-2
BK1A2M 2-Amino-4-fluoro-5-nitrobenzoic acid 1194097-41-0
BK04ZE N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine 314771-88-5
BK5L94 (E)-4-Bromobut-2-enoic acid 13991-36-1
BK3G98 (E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)but-2-enamide 1454655-89-0
BK82EZ (E)-4-((3-Chloro-4-fluorophenyl)amino)-7-fluoro-6-((4-(dimethylamino)but-2-enamido)quinazoline 1-oxide 1454656-00-8
BK2D23 (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1156986-96-7
BK75AW (S)-4-(Dimethylamino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide 1451008-28-8
BK8C2X (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451008-29-9
BK190V (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide mesylate 1451008-30-2
BK0T7T 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbamate 1451012-56-8
BK27ZJ (E)-4-(Dimethylamino)but-2-en-1-yl 4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbonate 1451012-57-9
BK6T31 7-Fluoro-4-((3-chloro-4-fluorophenyl)amino)-6-nitroquinazolin-3-ium chloride 1637330-92-7
BK0W74 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl 4-(dimethylamino)but-2-enoate 1637330-93-8
BK8Z98 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1-oxide 1451369-97-3
BK1K4D (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451369-98-4
Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
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