(E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)but-2-enamide CAS: 1454655-89-0

Product Parameters
Catalog No. BK3G98
CAS.RN 1454655-89-0
Molecular Formula C18H12BrClF2N4O
Molecular Weight 453.67 g/mol
Purity NLT 98%
Product Overview

(E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazoline-6-yl)but-2-enamide is a structurally complex pharmaceutical intermediate primarily used in the development of synthetic processes for innovative drugs such as antitumor and antiviral agents. This compound possesses a well-defined molecular structure and stable chemical properties, making it suitable for structural modification and activity screening in the early stages of drug development. It can also serve as a starting material for pilot-scale and large-scale production. It is widely used in new drug development, process optimization, and customized synthesis projects, meeting the needs of multiple stages from laboratory research to industrial production.

Applications
  • Drug molecule structure modification and activity research
  • Key intermediates for antitumor drug synthesis
  • Support for antiviral drug process development
  • Customized synthesis services for pharmaceutical intermediates
  • Process route optimization in new drug development
Quality & Supply Capability

English Name: (E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)but-2-enamide Properties: This product is an organic compound containing halogen, fluorophenyl, and quinazolin rings. It exhibits good thermal and chemical stability. Its core functional groups include bromine, fluorine, amino, and amide groups, making it suitable for various coupling reactions and structural modifications. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide sample supply, small-scale preparation, pilot-scale amplification, and customized batch production services. We can provide flexible supply solutions based on customer requirements for purity, impurity control, packaging specifications, delivery time, and quality documentation. At the same time, we provide technical support from laboratory research and development to scale-up production, helping customers advance process development, route optimization and project transformation, and ensuring efficient and compliant completion of the entire life cycle management of drug intermediates.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing professional synthesis and process development capabilities. Full-scale supply capability, covering from sample production to commercial mass production. Complete quality control documentation to ensure product compliance with international standards. Customized synthesis and packaging solutions can be provided according to customer needs. Process optimization technical support and project scale-up services are offered.

Intermediates of Afatinib
Catalog No. Product Name CAS
BA70B4 Afatinib API 850140-72-6
BK45Q2 (E)-4-(dimethylamino)but-2-enoic acid Hydrochloride 1130155-48-4
BK0P7B 2-(Dimethylamino)acetaldehyde 52334-92-6
BK26A4 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-17-1
BK57LQ 3-Chloro-4-fluoroaniline 367-21-5
BK9PS5 (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine 314771-76-1
BK6VV7 Methyl 3-amino-4-hydroxybenzoate 536-25-4
BK342Z (E)-4-(Dimethylamino)but-2-enoyl chloride 1056149-69-9
BK5Z6K 4-Hydroxybenzonitrile 767-00-0
BK9K90 4-Hydroxy-3-nitrobenzonitrile 3272-08-0
BK2Q99 6-Nitro-7-fluoro-4-hydroxyquinazoline 162012-43-3
BK853Z (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 2170273-18-2
BK1A2M 2-Amino-4-fluoro-5-nitrobenzoic acid 1194097-41-0
BK04ZE N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine 314771-88-5
BK5L94 (E)-4-Bromobut-2-enoic acid 13991-36-1
BK3G98 (E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)but-2-enamide 1454655-89-0
BK82EZ (E)-4-((3-Chloro-4-fluorophenyl)amino)-7-fluoro-6-((4-(dimethylamino)but-2-enamido)quinazoline 1-oxide 1454656-00-8
BK2D23 (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1156986-96-7
BK75AW (S)-4-(Dimethylamino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide 1451008-28-8
BK8C2X (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451008-29-9
BK190V (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide mesylate 1451008-30-2
BK0T7T 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbamate 1451012-56-8
BK27ZJ (E)-4-(Dimethylamino)but-2-en-1-yl 4-((3-chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl carbonate 1451012-57-9
BK6T31 7-Fluoro-4-((3-chloro-4-fluorophenyl)amino)-6-nitroquinazolin-3-ium chloride 1637330-92-7
BK0W74 4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl 4-(dimethylamino)but-2-enoate 1637330-93-8
BK8Z98 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide 1-oxide 1451369-97-3
BK1K4D (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-fluoroquinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride 1451369-98-4
Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
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