(3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide sulfate CAS: 1223405-08-0

Product Parameters
Catalog No. BK76Q4
CAS.RN 1223405-08-0
Molecular Formula C21H24F2N6O6S
Molecular Weight 526.51 g/mol
Purity NLT 98%
Synonyms Larotrectinib sulfate
Product Overview

This product is a pharmaceutical intermediate and a key structural unit in the synthesis of nucleoside analogues. It is widely used in the development and production of innovative drugs such as antiviral and antitumor drugs. Its core structure includes a pyrazolopyrimidine ring, a 2,5-difluorophenyl group, and a hydroxypyrrolidineamide group, exhibiting high structural specificity and reactivity, making it suitable for drug molecule skeleton construction and functional group modification. This compound can meet the needs of small-scale preparation, pilot-scale amplification, and commercial production in the R&D stage, and is an important raw material for the process development of novel nucleoside analogues.

Applications
  • Construction of nucleoside analogue molecular skeletons
  • Synthesis of antiviral drug intermediates
  • Development of key intermediates for antitumor drugs
  • Optimization of drug synthesis routes
  • Development and scale-up of innovative drug processes
Quality & Supply Capability

English Name: (3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide sulfate Properties: This product is a complex heterocyclic compound containing a chiral center, exhibiting good thermal and chemical stability. It contains multiple polar functional groups, making it suitable for various organic synthesis reactions with high reactivity and selectivity. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. Our company can provide sample supply, small-scale preparation, pilot-scale amplification, and customized batch production services. We offer flexible supply solutions based on customer requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. At the same time, it provides full-process technical support from laboratory research and development to scale-up production, helping customers complete process development, route optimization and project transformation, and ensuring efficient and compliant advancement of drug development.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing extensive experience in product development and manufacturing. Full-scale supply capabilities, covering all stages from laboratory to commercial production. Provides complete quality control documentation, including COA, HPLC, NMR, etc., ensuring controllable product quality. Supports customized needs, adjusting purity, impurity limits, and packaging specifications according to customer requirements. Provides process optimization technical support to assist customers in improving synthesis efficiency and yield. Offers scale-up support services to ensure a smooth transition from R&D to mass production.

Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting

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