Larotrectinib CAS: 1223403-58-4
| Product Parameters | |
|---|---|
| Catalog No. | BA194R |
| CAS.RN | 1223403-58-4 |
| Molecular Formula | C21H22F2N6O2 |
| Molecular Weight | 428.44 g/mol |
| Purity | NLT 98% |
| Synonyms | LOXO-101 |
Product Overview
Larotrectinib is a highly selective neurotrophic tyrosine kinase receptor (NTRK) inhibitor widely used in targeted cancer therapy, especially for patients with NTRK gene fusion-positive solid tumors. As an active pharmaceutical ingredient (API), this product is suitable for the entire process of drug development, process development, and commercial production, meeting diverse needs from laboratory pilot-scale trials to pilot-scale amplification and mass production. It is a key starting material in innovative drug development.
Applications
- Supply of active pharmaceutical ingredients (APIs) for targeted cancer therapy
- Compound support for NTRK gene fusion detection research
- Process development and optimization of innovative anti-tumor drugs
- Compound preparation for preclinical and clinical trials
- Customized synthesis and intermediate supply for pharmaceutical companies
Quality & Supply Capability
English Name: Larotrectinib Properties: This product is a white to off-white solid with good chemical stability. It has a nitrogen-containing heterocyclic structure and is readily soluble in organic solvents, making it suitable as a key intermediate in drug synthesis. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific details. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging Documentation Support: COA, MSDS, HPLC, NMR, etc. We provide sample supply, small-scale preparation, pilot-scale amplification, and customized batch production services for larotrectinib. We can provide flexible supply solutions based on customers' specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. Furthermore, we have a professional technical team that can provide customers with full-process technical support from laboratory research and development to large-scale production, helping them efficiently advance process development, route optimization, and project transformation.
Why Choose Bioncan
Focused on APIs, with extensive experience in supplying NTRK inhibitor compounds. Full-scale supply capabilities, covering all stages from laboratory to commercial production. Provide complete quality control documentation, including COA, MSDS, HPLC, NMR, etc. Support customized needs, adjusting purity, impurity limits, and packaging according to customer requirements. Comprehensive process optimization and scale-up technical support to ensure smooth progress of customer R&D and production.
Intermediates of Larotrectinib
| Catalog No. | Product Name | CAS |
|---|---|---|
| BA194R | Larotrectinib API | 1223403-58-4 |
| BK1UP3 | (R)-2-(2,5-Difluorophenyl)pyrrolidine | 1218935-59-1 |
| BK76Q4 | (3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide sulfate | 1223405-08-0 |
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting
For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 1223403-58-4, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.