Ponatinib CAS: 943319-70-8
| Product Parameters | |
|---|---|
| Catalog No. | BA485A |
| CAS.RN | 943319-70-8 |
| Molecular Formula | C29H27F3N6O |
| Molecular Weight | 532.56 g/mol |
| Purity | NLT 98% |
Product Overview
Ponatinib is a potent multi-target tyrosine kinase inhibitor primarily used to treat patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia who are resistant to or intolerant of other tyrosine kinase inhibitors. As an active pharmaceutical ingredient (API), ponatinib is widely used in drug development, process optimization, and large-scale production, suitable for laboratory-scale, pilot-scale, and commercial manufacturing scenarios, meeting the pharmaceutical industry's stringent requirements for high-purity, high-quality APIs.
Applications
- Synthesis of key intermediates in drug development
- Raw material supply for tyrosine kinase inhibitor antitumor drugs
- Preclinical research and formulation development support
- Pharmaceutical company process route optimization and technology upgrades
- Customized mass production and commercial supply
Quality & Supply Capability
English Name: Ponatinib Properties: White to off-white crystalline powder with good thermal stability. Its molecular structure contains a benzimidazole ring and a piperazine group, exhibiting strong biological activity and selectivity. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific requirements. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from laboratory sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. Simultaneously, we have a professional technical support team to provide customers with comprehensive technical support from the R&D stage to industrial production, helping customers efficiently advance process development and project transformation.
Why Choose Bioncan
Focused on APIs, with extensive experience in supplying pharmaceutical intermediates and APIs. Full-scale supply capabilities, covering all stages from laboratory to commercial production. Provides a complete quality control documentation system to ensure products meet international standards. Supports customized solutions to meet different customers' purity, packaging, and delivery requirements. Comprehensive process optimization and scale-up technical support to enhance customers' R&D efficiency and production conversion capabilities.
Intermediates of Ponatinib
| Catalog No. | Product Name | CAS |
|---|---|---|
| BA485A | Ponatinib API | 943319-70-8 |
| BK030Y | Ponatinib hydrochloride | 1114544-31-8 |
| BK7S77 | 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline | 694499-26-8 |
| BK0LW4 | 3-Ethynylimidazolo[1,2-b]pyridazine | 943320-61-4 |
| BK88AT | 3-Iodo-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide | 943320-50-1 |
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting
For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 943319-70-8, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.
