Sitagliptin CAS: 486460-32-6
| Product Parameters | |
|---|---|
| Catalog No. | BA2H50 |
| CAS.RN | 486460-32-6 |
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | 407.31 g/mol |
| Purity | NLT 98% |
| Synonyms | (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one |
Product Overview
Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, widely used in the treatment of type 2 diabetes as the core active ingredient in antidiabetic drugs. This product is primarily used in pharmaceutical research and development, small-scale preparation, pilot-scale amplification, and commercial production. It is suitable for both active pharmaceutical ingredient (API) supply and formulation development, meeting the needs of the entire lifecycle from laboratory research to large-scale production. It is an important intermediate and API in the pharmaceutical and chemical industry.
Applications
- Synthesis of active pharmaceutical ingredients (APIs) for the treatment of type 2 diabetes
- Compound screening and activity validation in pharmaceutical R&D institutions
- Formulation process development and optimization
- Pilot-scale amplification and commercial production support
- Customized synthesis and preparation of impurity reference standards
Quality & Supply Capability
English Name: Sitagliptin Properties: White to off-white crystalline powder with good thermal and chemical stability. Contains amide groups and a piperazine ring structure, readily soluble in organic solvents, suitable as the active ingredient for DPP-4 inhibitors. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide comprehensive sample supply, small-scale preparation, pilot-scale amplification, and customized batch production services. We can flexibly formulate supply solutions according to customer requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. Simultaneously, we provide full-process technical support from laboratory R&D to scale-up production, helping customers advance process development, route optimization, and project transformation, ensuring an efficient, compliant, and stable supply of active pharmaceutical ingredients.
Why Choose Bioncan
Specializing in DPP-4 inhibitor APIs, possessing professional R&D and manufacturing experience. Full-scale supply capability, covering all stages from laboratory to commercialization. Provides complete quality control documentation, complying with international pharmaceutical regulatory standards. Supports customized needs, adjusting purity, impurity control, and packaging specifications according to customer requirements. Provides supporting process optimization technology and project scale-up services to ensure smooth project progress for clients.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting
For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 486460-32-6, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.
