Tofacitinib CAS: 477600-75-2

Product Parameters
Catalog No. BA4R4H
CAS.RN 477600-75-2
Molecular Formula C3H3NO
Molecular Weight 69.06 g/mol
Purity NLT 98%
Product Overview

Tofacitinib is a selective JAK1/JAK3 inhibitor widely used in the field of rheumatology and immunology, primarily for the treatment of moderate to severe active rheumatoid arthritis and other autoimmune diseases. As an active pharmaceutical ingredient (API), tofacitinib is suitable for all stages of drug development, process optimization, and large-scale production, meeting diverse needs from laboratory trials to industrial-scale production. It is a key starting material in pharmaceutical intermediates and innovative drug development.

Applications
  • Rheumatoid arthritis drug development
  • Synthesis of drugs for autoimmune diseases
  • Customized manufacturing of pharmaceutical intermediates
  • Development of innovative drug process routes
  • Drug impurity research and control
Quality & Supply Capability

English Name: Tofacitinib Properties: White to off-white crystalline powder, readily soluble in organic solvents, exhibiting good thermal and chemical stability. Its core functional groups are a piperazine ring and a phenyl structure, meeting the physicochemical requirements of pharmaceutical raw materials. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from sample supply, small-scale preparation, pilot-scale amplification to customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Simultaneously, we have a professional technical support team to assist customers in completing the technical transition from laboratory research and development to industrial scale-up, ensuring smooth project progress and成果转化 (technology transfer).

Why Choose Bioncan

Focused on pharmaceutical raw materials, possessing a rich product line and industry experience. Full-scale supply capabilities, covering all stages from laboratory to commercialization. Provides complete quality control documentation to ensure product quality compliance and controllability. Supports customized needs, flexibly responding to the special requirements of different customers. Provides supporting process optimization and project scale-up technologies to help customers efficiently advance their R&D and production processes.

Products are offered for research, development, or industrial use only.
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting

For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 477600-75-2, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.