Afatinib CAS: 439081-18-2
| Product Parameters | |
|---|---|
| Catalog No. | BA974X |
| CAS.RN | 439081-18-2 |
| Molecular Formula | C24H25ClFN5O3 |
| Molecular Weight | 485.94 g/mol |
| Purity | 99% Min. |
| Synonyms | 850140-72-6 |
Product Overview
Afatinib is an irreversible tyrosine kinase inhibitor primarily used for targeted therapy of non-small cell lung cancer patients with EGFR mutations. It is a key intermediate and active pharmaceutical ingredient in anti-tumor drug development. This product is applicable across the entire pharmaceutical value chain, from research and development and process optimization to pilot-scale amplification and commercial production. It is widely used in innovative drug development and generic drug industrialization, exhibiting good stability and scalability to meet diverse needs from laboratory research to large-scale production.
Applications
- Synthesis of targeted therapies for non-small cell lung cancer
- Intermediates for anti-tumor drug development
- Drug process route optimization research
- Customized pharmaceutical synthesis services
- Supply of generic drug active pharmaceutical ingredients
Quality & Supply Capability
English Name: Afatinib Properties: White to off-white crystalline powder, readily soluble in organic solvents, with a stable molecular structure and well-defined functional groups, suitable for various synthetic routes. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific requirements. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches. Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging. Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from sample supply, small-scale preparation, pilot-scale amplification to customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. Simultaneously, we have a professional technical support team to provide customers with comprehensive technical support from laboratory R&D to scale-up production, helping customers efficiently advance process development, route optimization, and project transformation.
Why Choose Bioncan
Focus on supplying active pharmaceutical ingredients (APIs) for anti-tumor drugs, with comprehensive product coverage. Full-scale supply capabilities to meet needs from laboratory to commercial production. Provide complete quality control documentation to ensure product quality compliance and reliability. Support customized needs and flexibly address the technical requirements of different clients. Provide supporting process optimization and project scale-up technologies to improve client R&D efficiency.
Intermediates of Afatinib
| Catalog No. | Product Name | CAS |
|---|---|---|
| BA974X | Afatinib API | 439081-18-2 |
| BK685A | N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine | 162012-67-1 |
| BK7J2C | 7-fluoro-6-nitroquinazolin-4-ol | 162012-69-3 |
| BK8S7P | (S)-(+)-3-Hydroxytetrahydrofuran | 86087-23-2 |
| BK197F | 7-Chloro-6-nitroquinazolin-4(3H)-one | 53449-14-2 |
| BK070T | 7-Chloro-N-(3-chloro-4-fluorophenyl)-6-nitro-4-quinazolinamine | 179552-73-9 |
| BK2A7G | Trans-4-Dimethylaminocrotonic acid hydrochloride | 848133-35-7 |
| BK7R45 | Diethylphosphonoacetic Acid | 3095-95-2 |
| BK71MP | 2,2-Diethoxy-N,N-dimethylethylamine | 3616-56-6 |
Customers are responsible for ensuring compliance with applicable patent, regulatory, and import/export requirements in their respective jurisdictions.
Online Consulting
For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 439081-18-2, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.