Product Overview

Cis-(1R,3R)-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-B]indole-3-carboxylic acid methyl ester hydrochloride is a key pharmaceutical intermediate in the synthesis of tadalafil and is widely used in the process development and production of phosphodiesterase-5 (PDE5) inhibitors. This compound possesses a well-defined stereochemical structure and good reactivity, making it suitable for research and development, pilot-scale, pilot-scale, and large-scale production stages. It provides customers with a stable and reliable raw material supply, facilitating the construction of efficient and safe drug synthesis pathways.

Applications

• Synthesis of PDE5 inhibitors such as tadalafil
• Drug molecule structure modification and optimization research
• Customized synthesis project of pharmaceutical intermediates
• Process route development and validation
• Preclinical research and preparation for commercial production

Quality & Supply Capability

English Name: (1R,3R)-9h-pyrido[3,4-b]indole-3-carboxylicacid,1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride (Tadalafil Intermediates) Properties: This product is a white to off-white solid with a stable cyclic structure and specific substituent groups. It possesses good thermal and chemical stability and is suitable for various organic synthesis reaction systems. Storage Recommendations: Store in a sealed, light-protected, and dry place, subject to the specific COA/MSDS. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from laboratory sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documents. Meanwhile, we have a professional technical support team that can assist customers in process development, route optimization and project transformation, ensuring a seamless transition from R&D to mass production.

Why Choose Bioncan

Focused on pharmaceutical intermediates, possessing extensive synthesis experience and technological expertise. Full-scale supply capabilities to meet diverse needs from laboratory to commercial production. Comprehensive quality control documentation to ensure controllable and traceable product quality. Support for customized solutions, flexibly addressing the specific requirements of different clients. Support for process optimization and project scale-up technologies to enhance clients' R&D efficiency and production conversion rates.

Online Consulting

For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 171752-68-4, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.