Product Overview

1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is an important pharmaceutical intermediate widely used in the synthesis of the antiviral drug ledipasvir. As a key structural unit, this compound is suitable for synthetic exploration, small-scale preparation, pilot-scale amplification, and commercial production in the drug development stage. Its unique fluorinated and brominated structures endow it with excellent reactivity and stability, meeting the stringent requirements of modern drug synthesis for high purity and high stability, making it one of the important raw materials in the field of pharmaceutical intermediates.

Applications

• Synthesis of the antiviral drug Leadipasvir
• Customized synthesis of pharmaceutical intermediates
• Drug molecule structure modification and optimization
• Key starting materials in drug development
• Process route development and scale-up production

Quality & Supply Capability

English Name: 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone Properties: White to pale yellow crystalline powder with a fluorinated aromatic ring structure. It exhibits high chemical stability and reactivity, making it suitable for various organic synthesis reactions. Storage Recommendations: Store in a sealed, light-protected, and dry place, referring to the COA/MSDS for specific requirements. Supply Capabilities: Samples, gram-level, kilogram-level, commercial batches Packaging Specifications: Aluminum foil bags, fluorinated bottles, cardboard drums, customized packaging Document Support: COA, MSDS, HPLC, NMR, etc. We provide a full-process service from laboratory sample supply to small-scale preparation, pilot-scale amplification, and customized batch production. We can flexibly adjust the supply plan according to the customer's specific requirements for purity, impurity control, packaging specifications, delivery cycle, and quality documentation. Simultaneously, we have a professional technical team to provide customers with comprehensive technical support from laboratory R&D to industrial production, helping customers efficiently advance process development, route optimization, and project transformation.

Why Choose Bioncan

Focused on pharmaceutical intermediates, with extensive experience in drug synthesis. Full-scale supply capability, covering sample, pilot, pilot-scale, and commercial production. Provides complete quality control documentation to ensure product traceability. Supports customized needs, meeting personalized synthesis and process development requirements. Provides supporting process optimization and scale-up technologies to improve customer R&D efficiency.

Intermediates of Ledipasvir

Online Consulting

For quotation, inventory, samples, COA, MSDS, or custom synthesis support for CAS 1378387-81-5, please submit your requirements. We will respond according to purity, quantity, delivery timeline, and documentation needs.